Ontology highlight
ABSTRACT:
SUBMITTER: Swartz KJ
PROVIDER: S-EPMC1839852 | biostudies-literature | 2007 Feb
REPOSITORIES: biostudies-literature
Toxicon : official journal of the International Society on Toxinology 20060929 2
Voltage-activated ion channels open and close in response to changes in membrane voltage, a process that is crucial for electrical signaling in the nervous system. The venom from many poisonous creatures contains a diverse array of small protein toxins that bind to voltage-activated channels and modify the gating mechanism. Hanatoxin and a growing number of related tarantula toxins have been shown to inhibit activation of voltage-activated potassium (K(v)) channels by interacting with their volt ...[more]