Ontology highlight
ABSTRACT:
SUBMITTER: Tolun AA
PROVIDER: S-EPMC1839922 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Tolun Adviye A AA Dickerson Ian M IM Malhotra Arun A
Protein expression and purification 20060920 1
Calcitonin gene-related peptide (CGRP) is a neuropeptide secreted by the central and peripheral nervous system nerves that has important physiological functions such as vasodilation, cardiotonic actions, metabolic and pro-inflammatory effects. The CGRP receptor is unique among G-protein coupled receptors in that a functional CGRP receptor consists of at least three proteins: calcitonin like receptor (CLR), receptor activity modifying protein (RAMP1) and receptor component protein (RCP). RCP is a ...[more]