Misexpression screen in Drosophila melanogaster aiming to reveal novel factors involved in formation of body parts.
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ABSTRACT:
SUBMITTER: Grieder NC
PROVIDER: S-EPMC1855120 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
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Misexpression screen in Drosophila melanogaster aiming to reveal novel factors involved in formation of body parts.
Grieder Nicole C NC Charlafti Ilias I Kloter Urs U Jäckle Herbert H Schäfer Ulrich U Gehring Walter J WJ
Genetics 20061218 4
To identify novel factors that lead a fly imaginal disc to adopt its developmental fate, we carried out a modular dominant misexpression screen in imaginal discs. We have identified two factors that appear to change the fate of the respective body structure and appear to lead to the transformation of a body part. In one mutant line, notum tissue, normally derived from wing imaginal tissue, formed close to the site of the sternopleural bristles, which are leg disc derivatives. In the other line, ...[more]
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