Ontology highlight
ABSTRACT:
SUBMITTER: Komurov K
PROVIDER: S-EPMC1865589 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Molecular systems biology 20070424
In an effort to understand the dynamic organization of the protein interaction network and its role in the regulation of cell behavior, positioning of proteins into specific network localities was studied with respect to their expression dynamics. First, we find that constitutively expressed and dynamically co-regulated proteins cluster in distinct functionally specialized network neighborhoods to form static and dynamic functional modules, respectively. Then, we show that whereas dynamic module ...[more]