Ontology highlight
ABSTRACT:
SUBMITTER: Hipp K
PROVIDER: S-EPMC3326328 | biostudies-literature | 2012 Apr
REPOSITORIES: biostudies-literature
Nucleic acids research 20111213 7
Ribonuclease P (RNase P) and RNase MRP are closely related ribonucleoprotein enzymes, which process RNA substrates including tRNA precursors for RNase P and 5.8 S rRNA precursors, as well as some mRNAs, for RNase MRP. The structures of RNase P and RNase MRP have not yet been solved, so it is unclear how the proteins contribute to the structure of the complexes and how substrate specificity is determined. Using electron microscopy and image processing we show that eukaryotic RNase P and RNase MRP ...[more]