The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP.
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ABSTRACT:
SUBMITTER: Monne M
PROVIDER: S-EPMC1866048 | biostudies-literature | 2007 Apr
REPOSITORIES: biostudies-literature
Publications
The mimivirus genome encodes a mitochondrial carrier that transports dATP and dTTP.
Monné Magnus M Robinson Alan J AJ Boes Christoph C Harbour Michael E ME Fearnley Ian M IM Kunji Edmund R S ER
Journal of virology 20070117 7
Members of the mitochondrial carrier family have been reported in eukaryotes only, where they transport metabolites and cofactors across the mitochondrial inner membrane to link the metabolic pathways of the cytosol and the matrix. The genome of the giant virus Mimiviridae mimivirus encodes a member of the mitochondrial carrier family of transport proteins. This viral protein has been expressed in Lactococcus lactis and is shown to transport dATP and dTTP. As the 1.2-Mb double-stranded DNA mimiv ...[more]
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