Ontology highlight
ABSTRACT:
SUBMITTER: Rappsilber J
PROVIDER: S-EPMC186633 | biostudies-literature | 2002 Aug
REPOSITORIES: biostudies-literature
Genome research 20020801 8
In a previous proteomic study of the human spliceosome, we identified 42 spliceosome-associated factors, including 19 novel ones. Using enhanced mass spectrometric tools and improved databases, we now report identification of 311 proteins that copurify with splicing complexes assembled on two separate pre-mRNAs. All known essential human splicing factors were found, and 96 novel proteins were identified, of which 55 contain domains directly linking them to functions in splicing/RNA processing. W ...[more]