Recombination in feline lentiviral genomes during experimental cross-species infection.
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ABSTRACT:
SUBMITTER: Poss M
PROVIDER: S-EPMC1876777 | biostudies-literature | 2007 Mar
REPOSITORIES: biostudies-literature
Publications
Recombination in feline lentiviral genomes during experimental cross-species infection.
Poss Mary M Idoine Adam A Ross Howard A HA Terwee Julie A JA VandeWoude Sue S Rodrigo Allen A
Virology 20061012 1
Domestic cats develop an asymptomatic, productive infection with a feline immunodeficiency virus (PLV) derived from a naturally infected cougar (P. concolor). We previously demonstrated that there are extensive G to A substitutions, characteristic of host cytidine deaminase editing, and positive selection on reverse transcriptase in the PLV genome during this cross-species infection. In this study, we evaluated full-length viral genomes from each of four cats infected with PLV to determine if vi ...[more]
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