Ontology highlight
ABSTRACT:
SUBMITTER: Gladyshev EA
PROVIDER: S-EPMC1890498 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Proceedings of the National Academy of Sciences of the United States of America 20070504 22
The evolutionary origin of telomerases, enzymes that maintain the ends of linear chromosomes in most eukaryotes, is a subject of debate. Penelope-like elements (PLEs) are a recently described class of eukaryotic retroelements characterized by a GIY-YIG endonuclease domain and by a reverse transcriptase domain with similarity to telomerases and group II introns. Here we report that a subset of PLEs found in bdelloid rotifers, basidiomycete fungi, stramenopiles, and plants, representing four diffe ...[more]