Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1.
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ABSTRACT:
SUBMITTER: San Millan A
PROVIDER: S-EPMC1891367 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Publications
Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1.
San Millan Alvaro A Escudero Jose Antonio JA Catalan Ana A Nieto Silvia S Farelo Fidel F Gibert Magdalena M Moreno Miguel Angel MA Dominguez Lucas L Gonzalez-Zorn Bruno B
Antimicrobial agents and chemotherapy 20070416 6
beta-Lactam resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. Clinical high-level beta-lactam-resistant isolates from Spain bore a novel plasmid, pB1000, expressing a functionally active ROB-1 beta-lactamase. Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000. ...[more]
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