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Searching genomes for ribozymes and riboswitches.


ABSTRACT: New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes.

SUBMITTER: Hammann C 

PROVIDER: S-EPMC1895996 | biostudies-literature | 2007

REPOSITORIES: biostudies-literature

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Searching genomes for ribozymes and riboswitches.

Hammann Christian C   Westhof Eric E  

Genome biology 20070101 4


New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes. ...[more]

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