Ontology highlight
ABSTRACT:
SUBMITTER: Gray ES
PROVIDER: S-EPMC1900112 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Gray E S ES Moore P L PL Choge I A IA Decker J M JM Bibollet-Ruche F F Li H H Leseka N N Treurnicht F F Mlisana K K Shaw G M GM Karim S S Abdool SS Williamson C C Morris L L
Journal of virology 20070404 12
The study of the evolution and specificities of neutralizing antibodies during the course of human immunodeficiency virus type 1 (HIV-1) infection may be important in the discovery of possible targets for vaccine design. In this study, we assessed the autologous and heterologous neutralization responses of 14 HIV-1 subtype C-infected individuals, using envelope clones obtained within the first 2 months postinfection. Our data show that potent but relatively strain-specific neutralizing antibodie ...[more]