Ontology highlight
ABSTRACT:
SUBMITTER: Vidal-Ingigliardi D
PROVIDER: S-EPMC1913372 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Vidal-Ingigliardi Dominique D Lewenza Shawn S Buddelmeijer Nienke N
Journal of bacteriology 20070406 12
Apolipoprotein N-acyl transferase (Lnt) is an essential membrane-bound protein involved in lipid modification of all lipoproteins in gram-negative bacteria. Essential residues in Lnt of Escherichia coli were identified by using site-directed mutagenesis and an in vivo complementation assay. Based on sequence conservation and known protein structures, we predict a model for Lnt, which is a member of the CN hydrolase family. Besides the potential catalytic triad E267-K335-C387, four residues that ...[more]