Ontology highlight
ABSTRACT:
SUBMITTER: Quevillon-Cheruel S
PROVIDER: S-EPMC2253265 | biostudies-literature | 2005 May
REPOSITORIES: biostudies-literature
Quevillon-Cheruel Sophie S Leulliot Nicolas N Graille Marc M Hervouet Nadège N Coste Frank F Bénédetti Hélène H Zelwer Charles C Janin Joel J Van Tilbeurgh Herman H
Protein science : a publication of the Protein Society 20050331 5
Yhr049w/FSH1 was recently identified in a combined computational and experimental proteomics analysis for the detection of active serine hydrolases in yeast. This analysis suggested that FSH1 might be a serine-type hydrolase belonging to the broad functional alphabeta-hydrolase superfamily. In order to get insight into the molecular function of this gene, it was targeted in our yeast structural genomics project. The crystal structure of the protein confirms that it contains a Ser/His/Asp catalyt ...[more]