Ontology highlight
ABSTRACT:
SUBMITTER: Sangthong P
PROVIDER: S-EPMC1920251 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
Sangthong Padchanee P Hughes John J McCarthy John E G JE
Nucleic acids research 20070505 11
Protein synthesis utilizes a large proportion of the available free energy in the eukaryotic cell and must be precisely controlled, yet up to now there has been no systematic rate control analysis of the in vivo process. We now present a novel study of rate control by eukaryotic translation initiation factors (eIFs) using yeast strains in which chromosomal eIF genes have been placed under the control of the tetO7 promoter system. The results reveal that, contrary to previously published reports, ...[more]