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Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus.

ABSTRACT: One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the risks of detection bias and the omission of emerging MRSA clones.

SUBMITTER: Francois P

PROVIDER: S-EPMC1933053 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature

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Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus.

Francois Patrice P Bento Manuela M Renzi Gesuele G Harbarth Stephan S Pittet Didier D Schrenzel Jacques J

Journal of clinical microbiology 20070411 6

One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the risks of detection bias and the omission of emerging MRSA clones. ...[more]

PMID: 17428926

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