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Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus.


ABSTRACT: One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the risks of detection bias and the omission of emerging MRSA clones.

SUBMITTER: Francois P 

PROVIDER: S-EPMC1933053 | biostudies-literature | 2007 Jun

REPOSITORIES: biostudies-literature

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Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus.

Francois Patrice P   Bento Manuela M   Renzi Gesuele G   Harbarth Stephan S   Pittet Didier D   Schrenzel Jacques J  

Journal of clinical microbiology 20070411 6


One home-developed assay and two commercial assays for the rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) were compared by use of a collection of clinical isolates displaying highly diverse genetic backgrounds. Our results suggest that users of orfX-staphylococcal cassette chromosome mec-based assays should repeatedly monitor the local epidemiology to minimize the risks of detection bias and the omission of emerging MRSA clones. ...[more]

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