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In vivo development of quinolone resistance in Salmonella enterica serotype typhimurium DT104.

ABSTRACT: Salmonella enterica serotype Typhimurium definitive phage type 104 was isolated several times from the same patient over a period of 2 years. The strain developed reduced sensitivity to fluoroquinolones, and a mutation in the gyrA gene that is associated with reduced sensitivity to quinolones was identified.

SUBMITTER: Kristiansen MA

PROVIDER: S-EPMC193822 | biostudies-literature | 2003 Sep

REPOSITORIES: biostudies-literature

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In vivo development of quinolone resistance in Salmonella enterica serotype typhimurium DT104.

Kristiansen Malthe A Melau MA Sandvang Dorthe D Rasmussen Thorkild Bremholm TB

Journal of clinical microbiology 20030901 9

Salmonella enterica serotype Typhimurium definitive phage type 104 was isolated several times from the same patient over a period of 2 years. The strain developed reduced sensitivity to fluoroquinolones, and a mutation in the gyrA gene that is associated with reduced sensitivity to quinolones was identified. ...[more]

PMID: 12958295

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