Differential recognition of Plasmodium falciparum merozoite surface protein 2 variants by antibodies from malaria patients in Brazil.
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ABSTRACT:
SUBMITTER: Kanunfre KA
PROVIDER: S-EPMC193907 | biostudies-literature | 2003 Sep
REPOSITORIES: biostudies-literature
Publications
Differential recognition of Plasmodium falciparum merozoite surface protein 2 variants by antibodies from malaria patients in Brazil.
Kanunfre Kelly A KA Leoratti Fabiana M S FM Hoffmann Erika H E EH Durlacher Rui R RR Ferreira Antônio W AW Moraes-Avila Sandra L SL Ferreira Marcelo U MU
Clinical and diagnostic laboratory immunology 20030901 5
Four variants of merozoite surface protein 2 (MSP-2) of Plasmodium falciparum were used in serology to examine whether changes in repeat units affect its recognition by antibodies during infection with parasites of known MSP-2 types. The results indicate that variation in MSP-2 repeats may represent a mechanism for parasite immune evasion. ...[more]
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