Ontology highlight
ABSTRACT:
SUBMITTER: Pearce JA
PROVIDER: S-EPMC375173 | biostudies-literature | 2004 Apr
REPOSITORIES: biostudies-literature
Pearce J Andrew JA Triglia Tony T Hodder Anthony N AN Jackson David C DC Cowman Alan F AF Anders Robin F RF
Infection and immunity 20040401 4
Merozoite surface protein 1 (MSP1) is a highly polymorphic Plasmodium falciparum merozoite surface protein implicated in the invasion of human erythrocytes during the asexual cycle. It forms a complex with MSP6 and MSP7 on the merozoite surface, and this complex is released from the parasite around the time of erythrocyte invasion. MSP1 and many other merozoite surface proteins contain dimorphic elements in their protein structures, and here we show that MSP6 is also dimorphic. The sequences of ...[more]