Ontology highlight
ABSTRACT:
SUBMITTER: Schafer A
PROVIDER: S-EPMC1941761 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Schäfer Alexandra A Cai Xuezhong X Bilello John P JP Desrosiers Ronald C RC Cullen Bryan R BR
Virology 20070423 1
Several pathogenic human herpesviruses have recently been shown to express virally encoded microRNAs in infected cells. Although the function of these microRNAs is largely unknown, they are hypothesized to play a role in mediating viral replication by downregulating cellular mRNAs encoding antiviral factors. Here, we report the cloning and analysis of microRNAs encoded by Rhesus Monkey Rhadinovirus (RRV), an animal virus model for the pathogenic human gamma-herpesvirus Kaposi's Sarcoma-Associate ...[more]