Ontology highlight
ABSTRACT:
SUBMITTER: Umbach JL
PROVIDER: S-EPMC2923253 | biostudies-literature | 2010 Sep
REPOSITORIES: biostudies-literature
Umbach Jennifer L JL Strelow Lisa I LI Wong Scott W SW Cullen Bryan R BR
Virology 20100724 2
Rhesus rhadinovirus (RRV), a primate gamma-herpesvirus related to human Kaposi's sarcoma-associated herpesvirus (KSHV), causes a similar pattern of pathogenesis. Previously, RRV was shown to express 7 pre-microRNAs (pre-miRNAs) in latently infected cells. Using deep sequencing, we analyzed the pattern of small RNA expression in vivo using latently RRV-infected B-cell lymphoma and retroperitoneal fibromatosis tissues. We identified 15 virally encoded pre-miRNAs in both tumors, including all previ ...[more]