Ontology highlight
ABSTRACT:
SUBMITTER: Makarev E
PROVIDER: S-EPMC1941784 | biostudies-literature | 2007 May
REPOSITORIES: biostudies-literature
Makarev Evgeny E Call Mindy K MK Grogg Matthew W MW Atkinson Donald L DL Milash Brett B Odelberg Shannon J SJ Tsonis Panagiotis A PA
FEBS letters 20070409 9
Lens regeneration in adult newts is possible by transdifferentiation of the pigment epithelial cells (PECs) of the dorsal iris. The same cells in the ventral iris are not capable of such a process. To understand this difference in regenerative competency, we examined gene expression of 373 genes in the intact dorsal and ventral irises as well as in irises during the process of lens regeneration. We found similar signatures of gene expression in dorsal and ventral with several cases of even highe ...[more]