Ontology highlight
ABSTRACT:
SUBMITTER: Sousounis K
PROVIDER: S-EPMC3628982 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Sousounis Konstantinos K Looso Mario M Maki Nobuyasu N Ivester Clifford J CJ Braun Thomas T Tsonis Panagiotis A PA
PloS one 20130416 4
Regeneration of the lens in newts is quite a unique process. The lens is removed in its entirety and regeneration ensues from the pigment epithelial cells of the dorsal iris via transdifferentiation. The same type of cells from the ventral iris are not capable of regenerating a lens. It is, thus, expected that differences between dorsal and ventral iris during the process of regeneration might provide important clues pertaining to the mechanism of regeneration. In this paper, we employed next ge ...[more]