Ontology highlight
ABSTRACT:
SUBMITTER: Lodowski DT
PROVIDER: S-EPMC1950280 | biostudies-literature | 2007 Jun
REPOSITORIES: biostudies-literature
Lodowski David T DT Salom David D Le Trong Isolde I Teller David C DC Ballesteros Juan A JA Palczewski Krzysztof K Stenkamp Ronald E RE
Journal of structural biology 20070209 3
Oligomerization has been proposed as one of several mechanisms to regulate the activity of G protein-coupled receptors (GPCRs), but little is known about the structure of GPCR oligomers. Crystallographic analyses of two new crystal forms of rhodopsin reveal an interaction surface which may be involved in the formation of functional dimers or oligomers. New crystallization conditions lead to the formation of two crystal forms with similar rhodopsin-rhodopsin interactions, but changes in the cryst ...[more]