Expression of ephrinB1 and its receptor in glaucomatous optic neuropathy.
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ABSTRACT:
SUBMITTER: Schmidt JF
PROVIDER: S-EPMC1954885 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Publications
Expression of ephrinB1 and its receptor in glaucomatous optic neuropathy.
Schmidt Jimena F JF Agapova Olga A OA Yang Ping P Kaufman Paul L PL Hernandez M Rosario MR
The British journal of ophthalmology 20070214 9
<h4>Objective</h4>To determine ephrinB1, ephrinB2 and EphB1 expression in the optic nerve head (ONH) and retina of monkeys with glaucoma and in human ONH astrocytes.<h4>Methods</h4>Using immunohistochemistry, the localisation of ephrinB1, ephrinB2 and EphB1 was determined in the ONH and retina bilaterally in monkeys with monocular laser-induced glaucoma. RT-PCR, western blot and immunocytochemistry were used to study ephrinB1, ephrinB2 and EphB1 expression in cultured human ONH astrocytes from d ...[more]
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