Ontology highlight
ABSTRACT:
SUBMITTER: Miller MA
PROVIDER: S-EPMC195972 | biostudies-literature | 2003 Jan
REPOSITORIES: biostudies-literature
Miller Michael A MA Ruest Paul J PJ Kosinski Mary M Hanks Steven K SK Greenstein David D
Genes & development 20030101 2
During sexual reproduction in most animals, oocytes arrest in meiotic prophase and resume meiosis (meiotic maturation) in response to sperm or somatic cell signals. Despite progress in delineating mitogen-activated protein kinase (MAPK) and CDK/cyclin activation pathways involved in meiotic maturation, it is less clear how these pathways are regulated at the cell surface. The Caenorhabditis elegans major sperm protein (MSP) signals oocytes, which are arrested in meiotic prophase, to resume meios ...[more]