A metabolic sensor governing cell size in bacteria.
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ABSTRACT:
SUBMITTER: Weart RB
PROVIDER: S-EPMC1971218 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
Publications
A metabolic sensor governing cell size in bacteria.
Weart Richard B RB Lee Amy H AH Chien An-Chun AC Haeusser Daniel P DP Hill Norbert S NS Levin Petra Anne PA
Cell 20070701 2
Nutrient availability is one of the strongest determinants of cell size. When grown in rich media, single-celled organisms such as yeast and bacteria can be up to twice the size of their slow-growing counterparts. The ability to modulate size in a nutrient-dependent manner requires cells to: (1) detect when they have reached the appropriate mass for a given growth rate and (2) transmit this information to the division apparatus. We report the identification of a metabolic sensor that couples nut ...[more]
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