Ontology highlight
ABSTRACT:
SUBMITTER: Gallardo TD
PROVIDER: S-EPMC2013718 | biostudies-literature | 2007 Sep
REPOSITORIES: biostudies-literature
Gallardo Teresa D TD John George B GB Shirley Lane L Contreras Cristina M CM Akbay Esra A EA Haynie J Marshall JM Ward Samuel E SE Shidler Meredith J MJ Castrillon Diego H DH
Genetics 20070729 1
Female infertility syndromes are among the most prevalent chronic health disorders in women, but their genetic basis remains unknown because of uncertainty regarding the number and identity of ovarian factors controlling the assembly, preservation, and maturation of ovarian follicles. To systematically discover ovarian fertility genes en masse, we employed a mouse model (Foxo3) in which follicles are assembled normally but then undergo synchronous activation. We developed a microarray-based appr ...[more]