Ontology highlight
ABSTRACT:
SUBMITTER: Seagle BL
PROVIDER: S-EPMC4756718 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Seagle Brandon-Luke L BL Eng Kevin H KH Yeh Judy Y JY Dandapani Monica M Schiller Emily E Samuelson Robert R Odunsi Kunle K Shahabi Shohreh S
Scientific reports 20160217
Tumor mRNA expression was used to discover genes associated with worse survival or no survival benefit after intraperitoneal (IP) chemotherapy. Data for high grade serous ovarian cancer patients treated with IP (n = 90) or IV-only (n = 398) chemotherapy was obtained from The Cancer Genome Atlas. Progression free survival (PFS) and overall survival (OS) were compared between IP and IV groups using Kaplan-Meier analysis and Cox regression. Validations were performed by analyses of microarray and ...[more]