Ontology highlight
ABSTRACT:
SUBMITTER: Anderson MO
PROVIDER: S-EPMC2014784 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Anderson Marc O MO Wu Lisa Y LY Santiago Nicholas M NM Moser Jamie M JM Rowley Jennifer A JA Bolstad Erin S D ES Berkman Clifford E CE
Bioorganic & medicinal chemistry 20070811 21
A series of putative dipeptide substrates of prostate-specific membrane antigen (PSMA) was prepared that explored alpha- and beta/gamma-linked acidic residues at the P1 position and various chromophores at the P2 position, while keeping the P1' residue constant as L-Glu. Four chromophores were examined, including 4-phenylazobenzoyl, 1-pyrenebutyryl, 9-anthracenylcarboxyl-gamma-aminobutyryl, and 4-nitrophenylbutyryl. When evaluating these chromophores, it was found that a substrate containing 4-p ...[more]