Ontology highlight
ABSTRACT:
SUBMITTER: Martin G
PROVIDER: S-EPMC2040100 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Martin Georges G Keller Walter W
RNA (New York, N.Y.) 20070913 11
RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules. All rNTrs share a related active-site architecture first described for DNA polymerase beta and a catalytic mechanism conserved among DNA and RNA polymerases. The best known examples are the nuclear poly(A) polymerases involved in the 3'-end processing of eukaryotic messenger RNA precursors and the ubiquitous CCA-adding enzymes that compl ...[more]