Ontology highlight
ABSTRACT:
SUBMITTER: Paladino S
PROVIDER: S-EPMC2063760 | biostudies-literature | 2006 Mar
REPOSITORIES: biostudies-literature
Paladino Simona S Pocard Thomas T Catino Maria Agata MA Zurzolo Chiara C
The Journal of cell biology 20060320 7
The polarity of epithelial cells is dependent on their ability to target proteins and lipids in a directional fashion. The trans-Golgi network, the endosomal compartment, and the plasma membrane act as sorting stations for proteins and lipids. The site of intracellular sorting and pathways used for the apical delivery of glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are largely unclear. Using biochemical assays and confocal and video microscopy in living cells, we show that newl ...[more]