Ontology highlight
ABSTRACT:
SUBMITTER: Ding DQ
PROVIDER: S-EPMC2064256 | biostudies-literature | 2006 Aug
REPOSITORIES: biostudies-literature
Ding Da-Qiao DQ Sakurai Nobuko N Katou Yuki Y Itoh Takehiko T Shirahige Katsuhiko K Haraguchi Tokuko T Hiraoka Yasushi Y
The Journal of cell biology 20060807 4
The meiotic cohesin Rec8 is required for the stepwise segregation of chromosomes during the two rounds of meiotic division. By directly measuring chromosome compaction in living cells of the fission yeast Schizosaccharomyces pombe, we found an additional role for the meiotic cohesin in the compaction of chromosomes during meiotic prophase. In the absence of Rec8, chromosomes were decompacted relative to those of wild-type cells. Conversely, loss of the cohesin-associated protein Pds5 resulted in ...[more]