Ontology highlight
ABSTRACT:
SUBMITTER: Lin FL
PROVIDER: S-EPMC2072868 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
Lin Fiona L FL van Halbeek Herman H Bertozzi Carolyn R CR
Carbohydrate research 20070518 14
In this work, we describe the synthesis and NMR characterization of four mono- and four dideoxygenated analogs of alpha,alpha-D-trehalose. The symmetrical (2,2'-, 3,3'-, 4,4'- and 6,6'-) dideoxy analogs were obtained via selective protection and subsequent radical deoxygenation of the desired hydroxyl group set. The unsymmetrical (2'-, 3'-, 4'- and 6'-) monodeoxy analogs were synthesized by desymmetrization of alpha,alpha-trehalose and subsequent deoxygenation under radical conditions. Complete ...[more]