Ontology highlight
ABSTRACT:
SUBMITTER: Braun V
PROVIDER: S-EPMC2096587 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Braun Virginie V Deschamps Chantal C Raposo Graça G Benaroch Philippe P Benmerah Alexandre A Chavrier Philippe P Niedergang Florence F
Molecular biology of the cell 20071003 12
Phagocytosis, the mechanism of ingestion of large material and microorganisms, relies on actin polymerization and on the focal delivery of intracellular endocytic compartments. The molecular mechanisms involved in the formation and delivery of the endocytic vesicles that are recruited at sites of phagocytosis are not well characterized. Here we show that adaptor protein (AP)-1 but not AP-2 clathrin adaptor complexes are recruited early below the sites of particle attachment and are required for ...[more]