Gradual changes in hippocampal activity support remembering the order of events.
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ABSTRACT:
SUBMITTER: Manns JR
PROVIDER: S-EPMC2104541 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Publications
Gradual changes in hippocampal activity support remembering the order of events.
Manns Joseph R JR Howard Marc W MW Eichenbaum Howard H
Neuron 20071101 3
The hippocampus is thought to contribute to episodic memory in part by binding stimuli to their spatiotemporal context. The present study examined how hippocampal neuronal populations encode spatial and temporal context as rats performed a task in which they were required to remember the order of trial-unique sequences of odors. The results suggest that a gradual change in the pattern of hippocampal activity served as a temporal context for odor-sampling events and was important for successful s ...[more]
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