Borealin is repressed in response to p53/Rb signaling.
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SUBMITTER: Date DA
PROVIDER: S-EPMC2112748 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
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Borealin is repressed in response to p53/Rb signaling.
Date Dipali A DA Jacob Cara J CJ Bekier Mike E ME Stiff Andrew C AC Jackson Mark W MW Taylor William R WR
Cell biology international 20070715 12
Rb/E2F regulates many genes that encode proteins required for the cell cycle. Using affymetrix microarrays we previously identified genes regulated by the Rb proteins p130 and p107, many of which are involved in the cell cycle. Several genes with unknown functions were also repressed by p130 and p107, of which some have recently been found to have various roles in mitosis, the spindle checkpoint and cytokinesis. This study focuses on the regulation of borealin/dasra/cdca8, which encodes a recent ...[more]
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