Ontology highlight
ABSTRACT:
SUBMITTER: Martin-Padura I
PROVIDER: S-EPMC2133024 | biostudies-literature | 1998 Jul
REPOSITORIES: biostudies-literature
Martìn-Padura I I Lostaglio S S Schneemann M M Williams L L Romano M M Fruscella P P Panzeri C C Stoppacciaro A A Ruco L L Villa A A Simmons D D Dejana E E
The Journal of cell biology 19980701 1
Tight junctions are the most apical components of endothelial and epithelial intercellular cleft. In the endothelium these structures play an important role in the control of paracellular permeability to circulating cells and solutes. The only known integral membrane protein localized at sites of membrane-membrane interaction of tight junctions is occludin, which is linked inside the cells to a complex network of cytoskeletal and signaling proteins. We report here the identification of a novel p ...[more]