Ontology highlight
ABSTRACT:
SUBMITTER: Wang PJ
PROVIDER: S-EPMC2140218 | biostudies-literature | 1997 Dec
REPOSITORIES: biostudies-literature
The Journal of cell biology 19971201 5
Previously we isolated tub2-423, a cold-sensitive allele of the Saccharomyces cerevisiae gene encoding beta-tubulin that confers a defect in mitotic spindle function. In an attempt to identify additional proteins that are important for spindle function, we screened for suppressors of the cold sensitivity of tub2-423 and obtained two alleles of a novel gene, STU2. STU2 is an essential gene and encodes a protein whose sequence is similar to proteins identified in a variety of organisms. Stu2p loca ...[more]