Ontology highlight
ABSTRACT:
SUBMITTER: Hartmann C
PROVIDER: S-EPMC2168414 | biostudies-literature | 2007 Nov
REPOSITORIES: biostudies-literature
Hartmann Claudia C Benz Corinna C Brems Stefanie S Ellis Louise L Luu Van-Duc VD Stewart Mhairi M D'Orso Iván I Busold Christian C Fellenberg Kurt K Frasch Alberto C C AC Carrington Mark M Hoheisel Jörg J Clayton Christine E CE
Eukaryotic cell 20070914 11
In the African trypanosome Trypanosoma brucei nearly all control of gene expression is posttranscriptional; sequences in the 3'-untranslated regions of mRNAs determine the steady-state mRNA levels by regulation of RNA turnover. Here we investigate the roles of two related proteins, TbUBP1 and TbUBP2, containing a single RNA recognition motif, in trypanosome gene expression. TbUBP1 and TbUBP2 are in the cytoplasm and nucleus, comprise ca. 0.1% of the total protein, and are not associated with pol ...[more]