Ontology highlight
ABSTRACT:
SUBMITTER: Zou C
PROVIDER: S-EPMC2171251 | biostudies-literature | 2005 Nov
REPOSITORIES: biostudies-literature
The Journal of cell biology 20051101 3
In mammalian cells, the centrosome consists of a pair of centrioles and amorphous pericentriolar material. The pair of centrioles, which are the core components of the centrosome, duplicate once per cell cycle. Centrosomes play a pivotal role in orchestrating the formation of the bipolar spindle during mitosis. Recent studies have linked centrosomal activity on centrioles or centriole-associated structures to cytokinesis and cell cycle progression through G1 into the S phase. In this study, we h ...[more]