Ontology highlight
ABSTRACT:
SUBMITTER: Graser S
PROVIDER: S-EPMC2064767 | biostudies-literature | 2007 Oct
REPOSITORIES: biostudies-literature
The Journal of cell biology 20071001 2
Primary cilia (PC) function as microtubule-based sensory antennae projecting from the surface of many eukaryotic cells. They play important roles in mechano- and chemosensory perception and their dysfunction is implicated in developmental disorders and severe diseases. The basal body that functions in PC assembly is derived from the mature centriole, a component of the centrosome. Through a small interfering RNA screen we found several centrosomal proteins (Ceps) to be involved in PC formation. ...[more]