Ontology highlight
ABSTRACT:
SUBMITTER: Iomini C
PROVIDER: S-EPMC2172280 | biostudies-literature | 2004 Mar
REPOSITORIES: biostudies-literature
Iomini Carlo C Tejada Karla K Mo Wenjun W Vaananen Heikki H Piperno Gianni G
The Journal of cell biology 20040301 6
We identified primary cilia and centrosomes in cultured human umbilical vein endothelial cells (HUVEC) by antibodies to acetyl-alpha-tubulin and capillary morphogenesis gene-1 product (CMG-1), a human homologue of the intraflagellar transport (IFT) protein IFT-71 in Chlamydomonas. CMG-1 was present in particles along primary cilia of HUVEC at interphase and around the oldest basal body/centriole at interphase and mitosis. To study the response of primary cilia and centrosomes to mechanical stimu ...[more]