Ontology highlight
ABSTRACT:
SUBMITTER: Lenart P
PROVIDER: S-EPMC2172766 | biostudies-literature | 2003 Mar
REPOSITORIES: biostudies-literature
Lénárt Péter P Rabut Gwénaël G Daigle Nathalie N Hand Arthur R AR Terasaki Mark M Ellenberg Jan J
The Journal of cell biology 20030324 7
Breakdown of the nuclear envelope (NE) was analyzed in live starfish oocytes using a size series of fluorescently labeled dextrans, membrane dyes, and GFP-tagged proteins of the nuclear pore complex (NPC) and the nuclear lamina. Permeabilization of the nucleus occurred in two sequential phases. In phase I the NE became increasingly permeable for molecules up to approximately 40 nm in diameter, concurrent with a loss of peripheral nuclear pore components over a time course of 10 min. The NE remai ...[more]