Ontology highlight
ABSTRACT:
SUBMITTER: Dupuis-Williams P
PROVIDER: S-EPMC2173240 | biostudies-literature | 2002 Sep
REPOSITORIES: biostudies-literature
The Journal of cell biology 20020901 7
Centrioles and basal bodies fascinate by their spectacular architecture, featuring an arrangement of nine microtubule triplets into an axial symmetry, whose biogenesis relies on yet elusive mechanisms. However, the recent discovery of new tubulins, such as delta-, epsilon-, or eta-tubulin, could constitute a breakthrough for deciphering the assembly steps of this unconventional microtubule scaffold. Here, we report the functional analysis in vivo of epsilon-tubulin, based on gene silencing in Pa ...[more]