Ontology highlight
ABSTRACT:
SUBMITTER: McGraw S
PROVIDER: S-EPMC2190771 | biostudies-literature | 2007
REPOSITORIES: biostudies-literature
McGraw Serge S Morin Guillaume G Vigneault Christian C Leclerc Pierre P Sirard Marc-André MA
BMC developmental biology 20071102
<h4>Background</h4>Various histone acetylases (HATs) play a critical role in the regulation of gene expression, but the precise functions of many of those HATs are still unknown. Here we provide evidence that MYST4, a known HAT, may be involved in early mammalian gametogenesis.<h4>Results</h4>Although MYST4 mRNA transcripts are ubiquitous, protein expression was restricted to select extracts (including ovary and testis). Immunohistochemistry experiments performed on ovary sections revealed that ...[more]