Ontology highlight
ABSTRACT:
SUBMITTER: Moral R
PROVIDER: S-EPMC2200869 | biostudies-literature | 2007 Dec
REPOSITORIES: biostudies-literature
Moral Raquel R Wang Richard R Russo Irma H IH Mailo Daniel A DA Lamartiniere Coral A CA Russo Jose J
BMC genomics 20071206
<h4>Background</h4>Phthalate esters like n-butyl benzyl phthalate (BBP) are widely used plasticizers. BBP has shown endocrine-disrupting properties, thus having a potential effect on hormone-sensitive tissues. The aim of this study is to determine the effect of neonatal/prepubertal exposure (post-natal days 2-20) to BBP on maturation parameters and on the morphology, proliferative index and genomic signature of the rat mammary gland at different ages of development (21, 35, 50 and 100 days).<h4> ...[more]