Ontology highlight
ABSTRACT:
SUBMITTER: Malet H
PROVIDER: S-EPMC2222557 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Malet Hélène H Dalle Karen K Brémond Nicolas N Tocque Fabienne F Blangy Stéphanie S Campanacci Valérie V Coutard Bruno B Grisel Sacha S Lichière Julie J Lantez Violaine V Cambillau Christian C Canard Bruno B Egloff Marie Pierre MP
Acta crystallographica. Section F, Structural biology and crystallization communications 20060325 Pt 4
Macro domains or X domains are found as modules of multidomain proteins, but can also constitute a protein on their own. Recently, biochemical and structural studies of cellular macro domains have been performed, showing that they are active as ADP-ribose-1''-phosphatases. Macro domains are also present in a number of positive-stranded RNA viruses, but their precise function in viral replication is still unknown. The major human pathogen severe acute respiratory syndrome coronavirus (SARS-CoV) e ...[more]