Implications of rewiring bacterial quorum sensing.
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ABSTRACT:
SUBMITTER: Haseltine EL
PROVIDER: S-EPMC2223271 | biostudies-literature | 2008 Jan
REPOSITORIES: biostudies-literature
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Implications of rewiring bacterial quorum sensing.
Haseltine Eric L EL Arnold Frances H FH
Applied and environmental microbiology 20071126 2
Bacteria employ quorum sensing, a form of cell-cell communication, to sense changes in population density and regulate gene expression accordingly. This work investigated the rewiring of one quorum-sensing module, the lux circuit from the marine bacterium Vibrio fischeri. Steady-state experiments demonstrate that rewiring the network architecture of this module can yield graded, threshold, and bistable gene expression as predicted by a mathematical model. The experiments also show that the nativ ...[more]
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