Bacterial quorum sensing and metabolic incentives to cooperate.
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ABSTRACT:
SUBMITTER: Dandekar AA
PROVIDER: S-EPMC3587168 | biostudies-literature | 2012 Oct
REPOSITORIES: biostudies-literature
Publications
Bacterial quorum sensing and metabolic incentives to cooperate.
Dandekar Ajai A AA Chugani Sudha S Greenberg E Peter EP
Science (New York, N.Y.) 20121001 6104
The opportunistic pathogen Pseudomonas aeruginosa uses a cell-cell communication system termed "quorum sensing" to control production of public goods, extracellular products that can be used by any community member. Not all individuals respond to quorum-sensing signals and synthesize public goods. Such social cheaters enjoy the benefits of the products secreted by cooperators. There are some P. aeruginosa cellular enzymes controlled by quorum sensing, and we show that quorum sensing-controlled e ...[more]
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